Cancer, chronic fatigue and mental health

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XMRV, prostate cancer and chronic fatigue syndrome.

BACKGROUND A new retrovirus, xenotropic murine leukaemia virus-related virus (XMRV), was identified in 2006 and an association was claimed between it and a genetic polymorphism predisposing to cancer of the prostate. In 2009 the same virus was identified in a cohort of patients with chronic fatigue syndrome (CFS). In 2010 a second related virus was identified in a separate group of CFS patients...

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Are chronic fatigue and chronic fatigue syndrome valid clinical entities across countries and health-care settings?

OBJECTIVE The validity of the diagnosis of chronic fatigue syndrome and related chronic fatigue states remains controversial, particularly in psychiatry. This project utilized international epidemiological and clinical research data to test construct validity across diagnostic categories, health-care settings and countries. Relevant demographic, symptom and diagnostic data were obtained from 33...

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Implementing cognitive behavioral therapy for chronic fatigue syndrome in a mental health center: a benchmarking evaluation.

OBJECTIVE This study evaluated the success of implementing cognitive behavioral therapy (CBT) for chronic fatigue syndrome (CFS) in a representative clinical practice setting and compared the patient outcomes with those of previously published randomized controlled trials (RCTs) of CBT for CFS. METHOD The implementation interventions were the following: spreading information about the new tre...

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The Fatigued Brain: Associations of Chronic Fatigue and Acute Mental Fatigue on Resting-State Functional Connectivity

Fatigue is common among medical students and it is associated with impaired cognitive functions. In the present study we used fMRI to investigate intrinsic brain function associated with fatigue in medical students. We compared medical students with and without chronic fatigue (N = 25 per group, all females, mean age = 22 years). In addition, we manipulated acute fatigue and compared the groups...

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ژورنال

عنوان ژورنال: Occupational Medicine

سال: 2010

ISSN: 0962-7480,1471-8405

DOI: 10.1093/occmed/kqq012